AGENDA
VIRTUAL SESSIONS ARE NOT LIVE STREAMED. THEY WILL BE RECORDED AND PUBLISHED LATER FOR VIEWING.
Wednesday, November 8th
8:00am-10:20am
PLENARY SESSION 6 -
Regulation of Immune Cells/New Immune-Based Therapies
Salon A-F
Session Chair: John Kirkwood
Session available virtually
8:00am - 8:20am
Personalized Cancer Vaccines for Melanoma
Catherine Wu
8:20am - 8:35am
ACTengine IMA203 TCR-T targeting PRAME in PD1 refractory metastatic melanoma
Martin Wermke
8:35am - 8:55am
L-fucose: a dietary sugar to therapeutically alter tumor:immune interactions
Eric Lau
8:55am - 9:10am
NK cells can drive resistance to anti-PD1-based therapy in T-cell excluded melanoma
Joanna Pozniak
9:10am - 9:25am
Preliminary safety and efficacy from an open-label, multicenter, phase 1 study of RP2 as a single agent and in combination with nivolumab in a cohort of patients with uveal melanoma
Joseph Sacco
9:25am - 9:45am
Checkpoints, Cell Therapies, and Emerging Data
Sapna Patel
9:45am - 10:00am
Stratified analysis of checkpoint blockade regimens in metastatic melanoma leads to rational discovery of hypoxia-related targets in immune high tumors
Amy Huang
10:20am - 10:45am
Refreshment Break
10:45am - 12:30pm
CONCURRENT BREAKOUT 7A - Melanocyte Biology
Salon A-F
Session Chair: Corine Bertolotto
10:45am - 11:05am
20 Mins
Phenotype-switching in melanoma
Colin Goding
11:05am - 11:20am
15 Mins
Defining subpopulations of melanocytes in human skin
Bishal Tandukar
11:20am - 11:40am
20 Mins
Dissecting the magnitude and origin of melanoma plasticity and phenotypic diversity
Christophe Marine
11:40am - 11:55am
15 Mins
Melanocyte progenitor subpopulations in response to UV radiation and in vitiligo
Mark Shackleton
11:55am - 12:10pm
15 Mins
Characterizing how the skin microenvironment restrains melanoma progression
Yilun Ma
12:10pm - 12:30pm
20 Mins
Phenotype diversity and instability in healthy and transformed melanocytes
Robert Judson-Torres
10:45am - 12:30pm
CONCURRENT BREAKOUT 7B -
Genomics, Genetics and Epigenetics
Salon H-J
Session Chair: David Adams
10:45am - 11:05am
20 Mins
Invited Presentation
Boris Bastian
11:05am - 11:20am
15 Mins
Functional roles of enhancers in immune microenvironment and immunotherapy response
Kunal Rai
11:20am - 11:35am
15 Mins
CDS2 is an essential gene in uveal melanoma
Jenny Pui Ying Chan
11:35am - 11:50am
15 Mins
MacroH2A restricts inflammatory gene expression in melanoma cancer-associated fibroblasts by coordinating chromatin looping
Dan Filipescu
11:50am - 12:05pm
15 Mins
Investigation of the sexual dimorphic tumor suppressor role of DDX3X in melanoma
Marine Lingrand
12:05pm - 12:25pm
20 Mins
The generation of cancer specific ribosomes suppresses anti tumour immunity
Elenora Leucci
12:30pm - 2:00pm
Lunch - Exhibit and Poster Viewing
2:00pm - 3:15pm
PLENARY SESSION 8 -
Diversity and Inclusion in Melanoma Research
Salon A-F
Session Chair: Patricia Possik and Daniela Robles Espinoza
Session available virtually
Donita C. Brady, Ph.D: ‘Transforming the Culture and Climate in Cancer Research’
Gabriela Cinat: ‘Increasing Diversity in melanoma Clinical trials’
Susan M. Swetter, MD: ‘Improving health equity in melanoma prevention, early detection, and access to care’
2:00pm - 3:15pm
75 Mins
Increasing DEI in melanoma research: from bench to beside to community
Donita Brady, Gabriela Cinat and Susan Swetter
3:15pm - 3:45pm
Refreshment Break
3:45pm - 5:45pm
CONCURRENT BREAKOUT 9A -
Tumor Immune Microenvironment
Salon A-F
Session Chair: Julide Celebi
4 - Invited Faculty 3 - Oral Abstracts
3:45pm - 4:05pm
20 Mins
Metabolic regulation of melanoma tumor immunity
Bin Zheng
4:05pm - 4:20pm
15 Mins
HDAC8 promotes melanoma immune escape by increasing MDSC accumulation and decreasing T-cell recognition
Michael Emmons
4:20pm - 4:35pm
15 Mins
Electrical activity driven regulation of the melanoma microenvironment
Mohita Tagore
4:35pm -4:55pm
20 Mins
Lymph-borne, melanoma-derived proteins condition the lymph node for metastasis
Amanda Lund
4:55pm - 5:10pm
15Mins
Transglutaminase-2 expression is elevated in the invasive melanoma cell state and modulates the tumor immune microenvironment
Signe Caksa
5:10pm - 5:25pm
15 Mins
Tumor-Immune Profiling of Metastatic Melanoma Patients Reveals Biomarkers of Response to Combination Anti-LAG-3 + Anti-PD-1-based Immunotherapies
Tuba Gide
5:25pm - 5:45pm
20 Mins
Invited Presentation
Marisol Soengas
3:45pm - 5:35pm
CONCURRENT BREAKOUT 9B -
Population Studies/ Genetic Epidemiology
Salon H-J
Session Chair: Iman Osman
3:45pm - 4:05pm
20 Mins
Primary Melanoma DNA and Methylation Classes and Survival in the InterMEL Study
Nancy Thomas
4:05pm - 4:20pm
15 Mins
Functional characterization of non-coding CDKN2B variants found in high-risk melanoma families
Abigail Dennis
4:20pm - 4:40pm
20 Mins
Melanoma and CDKN2A: what have we learned in 30 years?
Alisa Goldstein
4:40pm - 4:55pm
15 Mins
Correlation of Family History of Auto-Immune disease and Immune Related Adverse Events: A Retrospective Study
Marcus Dempster
4:55pm - 5:15pm
20 Mins
Invited Presentation
Paolo Dotto
5:15pm - 5:35pm
20 Mins
The Interplay of host, microbial, and tumor metabolism: Obesity, diet, and immunotherapy responsse
Jennifer McQuade
7:00pm - 11:00pm
Awards Cermony - OffSite